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Search Results for " mtp inhibitor "

14

Compounds

Cat No. Product Name Synonyms Targets
T27719 KD-026 SLx 4090,SLx4090,KD026,SLx-4090 CETP
KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.
T31992 Granotapide CETP
Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an...
T30506 BMS-212122 UNII-0Z473OO6GB,BMS212122,BMS 212122 CETP
BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-212122 significantly reduced lipid content and monocyte-deriv...
T15006 Dirlotapide CP742033,Slentrol Others , CETP
Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by ...
T6267 Lomitapide AEGR-733,BMS-201038 CETP
Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring...
T2545 Lomitapide Mesylate BMS-201038 mesylate,AEGR-733 mesylate CETP
Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
T10504 Implitapide Racemate Others
Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T13418 CP-319340(free base) Others
CP-319340 free base is a inhibitor of microsomal triglyceride transfer protein (MTP) .
T15570 Implitapide AEGR 427 CETP
Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T16158 PF-02575799 Adenosine Receptor
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
T39303 CP-346086
CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces pl...
T38666 CP-346086 dihydrate
CP-346086 dihydrate is a potent and orally active inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM for both human and rodent MTP. This compound effectively lowers plasma cho...
T79602 MTP Autophagy
MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibits JAK2 signaling, rendering it useful for the study of ora...
T68588 CP-10447
CP-10447 is an inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study...
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